5 Simple Techniques For https://www.ceesdekker.net
5 Simple Techniques For https://www.ceesdekker.net
Blog Article
‘The next is nanopores, that's our oldest line of investigation and which has now resulted in DNA sequencers determined by nanopores. We pull specific DNA strands by way of a nanopore and may then study off the nucleotide sequence. Very not too long ago, we even managed to go through out just one protein for the first time using This system. But this line of exploration is not simply about establishing equipment, but additionally about genuine Organic issues.
But how can morality, the dignity on the human being, my working experience with the indicating of existence, adhere to within the motion of atoms? A purely naturalistic viewpoint fails here; a Christian point of view, I think, is a way more realistic method to interpret these areas of reality.’
[Laughs] ‘It had been surely an incredible threat! At time, I was nicely conscious that it could go Incorrect and that I could become significantly less thriving, but I just disregarded that. Curiosity has generally been my strongest driving drive. And by chance all of it worked out.’
Considering that 2000, Dekker has shifted the main target of his do the job towards biophysics wherever he research the Homes of one biomolecules and cells utilizing the tools of nanotechnology. This variation of subject was pushed by his fascination for the exceptional operating of Organic molecular buildings, as well as from the prolonged-expression standpoint that many fascinating discoveries could be envisioned During this field.[5] Present lines of analysis in his biophysics group are while in the regions of:[6]
This yielded a breakthrough. Within just a few months, we were in the position to measure transportation via somebody single-walled carbon nanotube. Based upon minimal-temperature experiments by a superb PhD pupil in my group, Sander Tans (now a valued colleague and professor at Delft University of Technology using an Lively analysis lab at AMOLF in Amsterdam), we confirmed that carbon nanotubes had been authentic quantum wires with very prolonged (micrometres) Digital coherence lengths — confirming theoretical predictions of metallic behaviour.
Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of a single wire bridging two electrodes
We use nanofabricated microfluidic constructions to pattern spatial boundaries for microorganisms and biomimetic vesicles with reconstituted protein networks and this evaluate the elemental purpose of spatial confinement for the molecular and mobile stage. Our initiatives incorporate the next:
Dynamic ParB–DNA interactions initiate and keep a partition condensate for bacterial chromosome segregation
‘Sure, I fully grasp persons have been surprised at some time. At https://www.ceesdekker.net the end of the nineties, Once i was in my forties, I had been Professor of Molecular Electronics and I have to confess that it had turn into a little bit bored, I didn’t discover Substantially any more. The sector went additional into the application aspect, how you could possibly integrate nanotubes into electronic circuits.
Right now, we also recognized that it should be feasible to make use of a single semiconducting carbon nanotube to make a transistor — and we established out to really make it. We stretched particular person semiconducting nanotubes across metallic electrodes and employed the underlying silicon substrate as being a gate electrode, establishing The essential 3-terminal format of a industry-outcome transistor (Fig.
Considering the fact that 2000 he moved to solitary-molecule biophysics and nanobiology, with study from experiments of DNA loop extrusion and supercoiling to DNA translocation by way of nanopores. Much more a short while ago his investigation has centered on finding out chromatin structure and cell division with bacteria on chip, when he can also be seeking to in the end Establish synthetic cells from The underside up.
Lots of new phenomena ended up found, and he and his research team established a number one position During this discipline of research. Dekker and his investigation group uncovered new physics of nanotubes in addition to explored the feasibility of molecular electronics. In 1998, they ended up the initial to make a transistor depending on a single nanotube molecule.
Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of only one wire bridging two electrodes
The biophysicist from Delft – who has long been One of the more cited experts while in the Netherlands For a long time – normally takes his obligation to lead on the explanation and popularisation of his work at the border of physics and biology exceptionally severely and often appears during the media; Otherwise to speak about his function, then about the relationship involving science and his Christian faith.